Endofluke (Triclabendazole)

Endofluke (Triclabendazole)

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Endofluke 100 mg/ml Oral Suspension is an orally administered drench used for the treatment of liver fluke in cattle and sheep. Endofluke 100 mg/ml fluke drench for cattle and sheep will treat mature, immature and early immature liver fluke (fasciola hepatica). Endofluke's active ingredient is triclabendazole which is the only active ingredient licensed in Ireland that has been proven to kill all three stages of liver fluke in sheep and cattle. Endofluke 100 mg/ml Oral Suspension has been approved for use in dairy cattle by the Irish Medicines Board (IMB).

Active Ingredient: Triclabendazole

Target Species: Cattle, sheep

Administration Method: Oral drench

Treats and Controls: Mature, immature and early immature liver fluke

Withdrawal Time: Animals should not be treated within 56 days of slaughter for human consumption. Cattle producing milk for human consumption need a withdrawl period of 48 hours after calving. Not intended for use within 45 days of calving. Should a cow calf earlier than 45 days after the last treatment, milk for human consumption may only be taken from 45 days plus 48 hours (47 days) after the last treatment.  Not permitted for use in sheep producing milk for human consumption.

Dosage for cattle: 6 ml per 50 kg of bodyweight

Body Weight Dose Volume Number of full doses per pack:
2.5 Litre 5 Litre
50kg 6 ml 416 833
100kg 12 ml 250 416
150kg 18 ml 138 277
200kg 24 ml 104 208
250kg 30 ml 83 166
300kg 36 ml 69 138
350kg 42 ml 59 119
400kg 48 ml 52 104
450kg 54 ml 46 92
500kg 60 ml 41 83
550kg 66 ml 37 75
600kg 72 ml 34 69
Animals over 600 kg give an aditional 6 ml per 50 kg 

Dosage for sheep:1ml per 10kg Bodyweight

Dosage Rates For Sheep
Body Weight Dose Volume Number of full doses per pack:
2.5 Litre 5 Litre
10kg 1ml 2500 5000
20kg 2 ml 1250 2500
30kg 3 ml 833 1666
40kg 4 ml 625 1250
50kg 5 ml 500 1000
60kg 6 ml 416 833
70kg 7 ml 357 714
Animals over 70 kg give an additional 1 ml per 10 kg 

Always read the label and all enclosed information for Endofluke Oral Suspension before administering to animals!

What are the effects of liver fluke infection?

  • Oedema under the jaw (bottle jaw)
  • Anaemia
  • Diarrhoea
  • Poor coat or poor wool production
  • Lack of appetite
  • Weight loss
  • Reduction in rate of growth.
  • Decrease in fertility
  • Decrease of milk yield
  • In severe cases liver fluke can even cause death

Key Features ofEndofluke100 mg/ml Oral Suspension

  • Kills three stages of liver fluke. Early immature, mature and adult
  • Tried and tested triclabendazole formula that is trusted by farmers
  • Complete chronic and acute fluke control in both cattle and sheep
  • Low volume dose establishes a quick and accurate dosing regime

What else can I do to help prevent liver fluke?

  • Make sure you have proper drainage on your land.
  • Where possible fence off wet areas.
  • Prevent grazing on "flukey areas".
  • Dose bought in animals before introducing them to pastures.
  • Dose animals mid summer to reduce the presence of liver fluke while grazing.
  • Dose animals at housing and if required four to six weeks later.

​This product is only licensed for sale within the Republic of Ireland

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